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@pinellolab

Pinello Lab

Massachusetts General Hospital/Harvard Medical School

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  1. STREAM STREAM Public

    STREAM: Single-cell Trajectories Reconstruction, Exploration And Mapping of single-cell data

    Jupyter Notebook 168 45

  2. CRISPResso2 CRISPResso2 Public

    Analysis of deep sequencing data for rapid and intuitive interpretation of genome editing experiments

    Python 256 91

  3. haystack_bio haystack_bio Public

    Haystack: Epigenetic Variability and Transcription Factor Motifs Analysis Pipeline

    HTML 44 10

  4. CRISPR-SURF CRISPR-SURF Public

    Python 15 3

  5. PrimeDesign PrimeDesign Public

    Software tool for the flexible design of pegRNAs and ngRNAs for prime editing!

    Python 20 6

  6. MotifRaptor MotifRaptor Public

    Explore the effect of genetic variants on transcription factor binding sites

    Python 7 2

Repositories

Showing 10 of 48 repositories
  • pyrovelocity Public

    𝒫robabilistic modeling of RNA velocity ⬱

    pinellolab/pyrovelocity’s past year of commit activity
    Python 37 AGPL-3.0 5 2 15 Updated Jul 1, 2024
  • ACCESS-ATAC-seq Public

    Scripts for ACCESS-ATAC-seq data

    pinellolab/ACCESS-ATAC-seq’s past year of commit activity
    Python 0 MIT 0 0 0 Updated Jun 27, 2024
  • CRISPRme Public
    pinellolab/CRISPRme’s past year of commit activity
    Python 16 8 3 0 Updated Jun 27, 2024
  • crispr-bean Public

    Activity-normalized variant effect size estimation from pooled CRISPR screens

    pinellolab/crispr-bean’s past year of commit activity
    Python 8 AGPL-3.0 2 1 0 Updated Jun 25, 2024
  • perturb-tools Public

    Analysis Framework for Pooled CRISPR Genome Editing Screens

    pinellolab/perturb-tools’s past year of commit activity
    Jupyter Notebook 1 MIT 0 0 0 Updated Jun 25, 2024
  • CRISPR-millipede-sgRNA Public

    Perform CRISPR guide mapping and analysis that considers protospace self-editing and surrogate sensor sequences. Self-editing aware mapping takes a hamming-distance approach unbiased by expectations in editing patterns.

    pinellolab/CRISPR-millipede-sgRNA’s past year of commit activity
    Python 0 0 2 0 Updated Jun 25, 2024
  • CRISPResso2 Public

    Analysis of deep sequencing data for rapid and intuitive interpretation of genome editing experiments

    pinellolab/CRISPResso2’s past year of commit activity
    Python 256 91 28 4 Updated Jun 20, 2024
  • DNA-Diffusion Public

    🧬 Generative modeling of regulatory DNA sequences with diffusion probabilistic models 💨

    pinellolab/DNA-Diffusion’s past year of commit activity
    Jupyter Notebook 351 48 5 10 Updated Jun 16, 2024
  • CRISPR-millipede-pipelines Public

    Repository contains the pipeline scripts and resources for running tools in the CRISPR-millipede suite at scale.

    pinellolab/CRISPR-millipede-pipelines’s past year of commit activity
    WDL 0 0 0 0 Updated Jun 13, 2024
  • Xeno-share Public

    Script for xenograft SHARE-seq data

    pinellolab/Xeno-share’s past year of commit activity
    Python 0 MIT 0 0 0 Updated Jun 7, 2024