This is a combined resource of 5 publications that looked at human imprinting:
| Publication | Tissue-specificity |
|---|---|
| Court et al. 2014 | Placental + Other |
| Hanna et al. 2016 | Placental + Other |
| Sanchez-Delgado et al. 2016 | Placental |
| Hamada et al. 2016 | Placental |
| Zink et al. 2018 | Other |
These regions can be found in @ processed/all_imprinted_dmrs.tsv
Here is a view of the first 6 rows:
| chr | start | end | methylated\_allele | tissue\_specificity | associated\_gene | court | hanna | sanchez\_delgado | zink | hamada | note |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 6684860 | 6685996 | M | placental-specific | THAP3 | NA | TRUE | NA | NA | NA | NA |
| 1 | 7827139 | 7827709 | M | other | NA | NA | NA | NA | TRUE | NA | NA |
| 1 | 19614429 | 19615702 | M | placental-specific | AKR7A3 | NA | TRUE | NA | NA | NA | NA |
| 1 | 36184400 | 36184863 | M | placental-specific | C1orf216 | NA | TRUE | NA | NA | NA | NA |
| 1 | 38200920 | 38201123 | M | other | EPHA10 | NA | TRUE | NA | NA | NA | NA |
| 1 | 39559602 | 39559980 | M | other | PPIEL | NA | NA | NA | TRUE | NA | NA |
There are in total 418 imprinted regions, which can be divided into those that are specific to the placenta, and those that have been observed in other tissues.
| tissue\_specificity | n |
|---|---|
| other | 307 |
| placental-specific | 111 |